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Halted Swiss study of Canadian Ebola vaccine resumes with lower dose

Canada announced it would start to ship an experimental Ebola vaccine to the World Health Organization in Geneva starting Oct. 20, 2014. HANDOUT/Public Health Agency of Canada

A Swiss trial of a Canadian-made Ebola vaccine has resumed after being suspended because of concerns about an unexpected side-effect.

Dr. Angela Huttner says the research team started vaccinating new volunteers this week after a break of several weeks called to investigate the problem.

The study was temporarily stopped in mid-December after several volunteers reported having joint pain in fingers or toes about 14 days after receiving the vaccine.

Huttner says an investigation into the cases has led the researchers to conclude that the pain was a side-effect of receiving the vaccine.

She says the dose being used has been adjusted and is now much lower than what was being given in the first part of the trial.

The trial, which is being conducted at University Hospitals of Geneva, is expected to enrol its full complement of volunteers by the end of January.