A man in his 40s is in life-threatening condition after being struck by a vehicle on Lake Shore Blvd. E. and Coxwell Ave.
Paramedics were called to the area before 9:30 p.m. Sunday night and rushed the man to a trauma centre in an emergency run.
Toronto police say the driver remained on scene.
Eastbound Lake Shore is closed from Northern Dancer to Coxwell for the investigation.